New Keywords in the Treatment of Malignant Pleural Mesothelioma

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Diagnosis and treatment of malignant pleural mesothelioma.

There are three major challenges in the diagnosis of malignant pleural mesothelioma: mesothelioma must be distinguished from benign mesothelial hyperplasia; malignant mesothelioma (and its subtypes) must be distinguished from metastatic carcinoma; and invasion of structures adjacent to the pleura must be demonstrated. The basis for clarifying the first two aspects is determination of a panel of...

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Diagnosis and Treatment of Malignant Pleural Mesothelioma

There are three major challenges in the diagnosis of malignant pleural mesothelioma: mesothelioma must be distinguished from benign mesothelial hyperplasia; malignant mesothelioma (and its subtypes) must be distinguished from metastatic carcinoma; and invasion of structures adjacent to the pleura must be demonstrated. The basis for clarifying the first two aspects is determination of a panel of...

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The Role of Immunohistochemistry Studies in Distinguishing Malignant Mesothelioma from Metastatic Lung Carcinoma in Malignant Pleural Effusion

Background and Objective: Early diagnosis of malignant pleural mesothelioma (MPM) is the key point of its treatment. The main problem is the precise diagnosis of mesothelioma and its differentiation from metastatic lung adenocarcinoma. Mesothelioma exhibits complex immunohistochemical characteristics. The aim of this study was to study hybrid immunohistochemistry in the differe...

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Pemetrexed in the treatment of malignant pleural mesothelioma

Malignant pleural mesothelioma (MPM) is a relatively uncommon tumor that is increasing in frequency in most areas of the world. For example, in the UK there has been a sharp increase in the number of cases since the late 1970s, a trend which is predicted to reach its peak by approximately 2015, when over 2000 cases per annum are likely to be diagnosed [1]. It is a tumor which is, in the vast ma...

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Pleuropneumonectomy in the treatment of malignant pleural mesothelioma.

STUDY OBJECTIVES Malignant pleural mesothelioma (MPM) is predominantly a local/regional disease that results in a survival time that ranges from 4 to 12 months without treatment. Single-modality therapy using surgery, chemotherapy, or radiotherapy alone is largely ineffective. The objective of the study was presentation of the use of pleuropneumonectomy in a multimodality treatment setting and ...

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ژورنال

عنوان ژورنال: The Annals of Thoracic Surgery

سال: 2017

ISSN: 0003-4975

DOI: 10.1016/j.athoracsur.2016.12.007